In order to profile a Web Application using Internet Information Services, you should just run the profiler and it will attach itself to Internet Information Services. It is important to note that when profiling applications using Internet Information Services, dotMemory needs to be run on behalf of Administrator (In Windows Vista, 7 or 8, right-click the dotMemory icon and select Run as administrator).
Optionally you can specify the following parameters:
Run Browser If you check this option, you can provide additional properties:
Url The Url to invoke the web application.
Browser A browser that should run the application you profile. The default system browser is pre-selected.