PyCharm integrates with tox and allows running tests in multiple environments.
Use tox integration
Install tox for the project interpreter.
Specify tox as a dedicated test runner for your project.
Ensure that your project has the following files:
Right-click the file tox.ini and choose Run. The dedicated tox run/debug configuration is launched.
The results show up in the test runner tab of the Run tool window:
Right-click any test result in the Test Runner to execute tox in a particular environment: