ReSharper enables you to use ReSharper's Basic completion in automatic IntelliSense popup and when pressing Control+Space. The Parameter Information will also replace the corresponding Visual Studio feature.
Visual Studio preserves the Visual Studio's native behavior for automatic IntelliSense popup and for the Control+Space shortcut. However, you can still use ReSharper's smart completion and import symbol completion features.
Custom IntelliSense is similar to the first option, but it allows you to specify languages where ReSharper IntelliSense features apply.